USB-6421

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$999.00

USB-6421 (OEM), 16-bit, 250kS/s (16AI, 2AO, 16DIO), 50-pin connector, mioDAQ Device

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National Instruments USB-6421 X Series Multifunction USB DAQ Device for High-Speed Data Acquisition and Testing

NI USB-6421 X Series Multifunction USB DAQ Device

The NI USB-6421 is a high-performance X Series multifunction USB data acquisition (DAQ) device designed for advanced measurement, automated testing, electronic validation, and industrial research applications. Developed by National Instruments, the USB-6421 combines analog input, analog output, digital I/O, and counter/timer functions into a flexible USB-based measurement platform.

Based on NI X Series DAQ technology, the USB-6421 provides high-speed acquisition, accurate timing, and flexible I/O capability for engineers developing complex measurement and automation systems. It delivers reliable performance without requiring a PXI chassis.

With NI-DAQmx driver support, LabVIEW compatibility, and USB connectivity, the USB-6421 enables users to create scalable test and measurement solutions for laboratory, industrial, and engineering applications.

Key Features of NI USB-6421

Multifunction X Series DAQ Architecture

The USB-6421 integrates multiple measurement functions into one compact USB DAQ platform.

  • Analog input measurement
  • Analog output generation
  • Digital input and output
  • Counter/timer functionality
  • Multifunction acquisition capability

High-Speed Analog Data Acquisition

The USB-6421 provides accurate and reliable analog measurement capability for demanding applications.

  • High-speed signal acquisition
  • Multi-channel voltage measurement
  • Synchronized data collection
  • Engineering signal analysis

Advanced Timing and Synchronization

The USB-6421 supports hardware timing and synchronization features for complex measurement systems.

  • Hardware-timed acquisition
  • Trigger control
  • Counter operations
  • Synchronized measurement

Flexible Digital I/O Capability

The USB-6421 provides digital control capability for automation and external device integration.

  • Digital signal monitoring
  • Device control
  • Automation interface
  • External hardware connection

NI Software Support

The USB-6421 works with NI software platforms for complete measurement application development.

  • LabVIEW support
  • NI-DAQmx driver support
  • NI MAX configuration
  • TestStand integration

Applications of NI USB-6421

Automated Test Equipment

The USB-6421 provides flexible acquisition and control capability for automated testing systems.

  • Electronic product testing
  • Functional verification
  • Production test systems
  • ATE development

Electronic Design Verification

The USB-6421 helps engineers validate hardware designs through accurate measurement and analysis.

  • Prototype testing
  • Signal monitoring
  • Hardware validation
  • Engineering analysis

Industrial Measurement

The USB-6421 supports industrial applications requiring reliable data acquisition and control.

  • Process monitoring
  • Machine testing
  • Industrial automation
  • Equipment diagnostics

Laboratory Research

The USB-6421 provides a flexible platform for scientific experiments and engineering research.

  • Experimental measurement
  • Sensor acquisition
  • Data analysis
  • Prototype development

Software Support

The NI USB-6421 supports National Instruments software tools for advanced DAQ development.

  • LabVIEW
  • NI-DAQmx
  • NI MAX
  • TestStand

Technical Specifications of USB-6421

FeatureDescription
Product TypeX Series Multifunction USB DAQ Device
PlatformUSB DAQ
DAQ FamilyX Series
FunctionsAnalog Input, Analog Output, Digital I/O, Counter/Timers
ConnectivityUSB Interface
SoftwareLabVIEW, NI-DAQmx
ApplicationsTesting, measurement, automation, research

Comparison with Similar USB DAQ Devices

ModelMain DifferenceBest Application

NI USB-6421
High-performance multifunction USB DAQ device combining analog, digital, and timing functions. Advanced measurement systems

NI USB-6341
X Series USB DAQ device designed for general automated measurement applications. General testing

NI USB-6343
Higher-channel USB DAQ device for complex multi-channel acquisition. Industrial and laboratory systems

NI USB-6361
Higher-performance X Series USB DAQ device for advanced high-speed applications. High-speed testing

Recommended Related Products

The following products are commonly used with the USB-6421 to build complete data acquisition and automated test systems.


NI USB-6363
High-speed X Series USB DAQ device for advanced acquisition and automated testing.

NI USB-6343
Multifunction USB DAQ device for flexible measurement and automation applications.

NI PXIe-6421
PXI Express DAQ module for modular high-performance test systems.

NI cDAQ-9178
CompactDAQ chassis for modular sensor measurement and industrial acquisition.

NI USB-6002
Entry-level USB DAQ device for basic measurement and education applications.

Why Choose NI USB-6421

  • High-performance multifunction USB DAQ capability
  • Flexible analog and digital measurement functions
  • Advanced timing and synchronization
  • Supports LabVIEW and NI-DAQmx
  • Easy USB system integration
  • Ideal for automated testing and engineering measurement

Conclusion

The NI USB-6421 X Series Multifunction USB DAQ Device provides a flexible and powerful measurement solution for engineers requiring reliable data acquisition and control capability.

With multifunction I/O, USB connectivity, advanced timing features, and NI software support, the USB-6421 is an excellent choice for automated testing, industrial measurement, electronic validation, and research applications.

Part Number(s): 789887-01 | 789885-01

Specifications

Supported Power Input: Bus Powered
Maximum Number of Single-Ended Analog Input Channels: 16
Maximum Number of Differential Analog Input Channels: 8
Maximum Sample Rate: 250 kS/s
Simultaneous Sampling: No
Analog Input Resolution: 16 bits
Bus Connector: USB C
Number of Analog Output Channels: 2
Maximum Update Rate: 250 kS/s
Number of Bidirectional Digital Channels: 16
Number of Counters/Timers: 4
Analog Input Absolute Accuracy: 2.61 mV
Analog Input FIFO Buffer Size: 8191 samples
Analog Input Isolation: –

Brand

National Instruments

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